在染色体10的v38位置,由ENU诱导的T到C的转换,对应于基因NC_000076在GenBank的基因组区域中的第8,368个碱基,或者说是Myb基因的第21,152,617个碱基对。这个变异等同于mRNA序列NM_010848中第612位的氨基酸,位于第5个外显子的15个总外显子中,导致丝氨酸(S)变为脯氨酸(P),即S116P的替换。(来源:J:265264)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
半显性
1
4
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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