在第六号染色体的v38版本(基对12,256,867)由ENU诱导的G到A的转换,或者在GenBank的NC_000072基因组区域的第8,059位,对应于Aicda编码序列。这个变异对应于mRNA序列NM_009645中第4个外显子的第547位氨基酸(547位的V到I替换)。AID蛋白的这个改变会导致第152位的Valine被Isoleucine取代。(来源:J:265155)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
隐性
1
1
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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