Vav1^m2Btlr

ENU-induced G to A transition at base pair 57,297,122 (v38) on chromosome 17, or base pair 18,044 in the GenBank genomic region NC_000083. The mutation corresponds to residue 621 in the mRNA sequence NM_011691 within exon 5 of 27 total exons. The mutation results in a glutamic acid to lysine substitution at amino acid 175 (E175K) in the VAV1 protein. (J:265130)