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中文
Akap5CS突变通过将Cysteines 36和123替换为Serines，移除了AKAP150的棕榈酰化。这种突变是在C57BL/6小鼠BAC克隆的一个单一编码exon中，通过piggyBac（PB）转座子系统导入的Akap5基因DNA片段。在该导向载体中，PB方法同时引入了CS突变和一个C末端的myc标签，周围是带有Neo抗性基因，该基因由PB的3和5长末端重复（LTR）序列包裹，插入到了Akap5的exon内。随后，通过表达PB转座酶短暂激活，将Neo抗性基因从靶位点移除。来源：(J:269375)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
