在exon 4的上游插入了loxP位点和FRT引导的neo cassette,通过同源重组,又在exon 5的下游插入了loxP位点。通过Flp介导的重组,去除了neo cassette,使得exons 4和5被标记为可删除的。(来源:J:264514)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count