人类黑皮质素1受体(RHC变异型,p.Arg151Cys或p.R151C)的基因被放置在小鼠酪氨酸酶增强子/启动子下游。牛生长激素的poly(A)信号序列被置于人类基因之后。转基因构建被注入来自Mc1r敲除小鼠产生的含有Mc1re等位基因的卵子中。(来源:J:252840)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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