Log In|Sign Up
中文
在exon 5的第178位，精氨酸密码子被替换为终止密码子TAA，通过sgRNA和一个183nt单链DNA模板，利用CRISPR/Cas9技术实现。为诊断目的，随后在该位置插入了两个额外的替换，形成了EcoRI酶切位点。这个变异的基因编码为NM_001200038.1:c.562_569delinsTAAGAAT。所有必需的成分被注入了C57BL/6胚胎的细胞质中。(来源：J:261225)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
