An inversion was generated between the regions targeted by sgRNAs 5'-GAGATTCTACTCCTAAGCCC-3' and 5'-ATTCCCCGGGAAATAGCCCA-3', using CRISPR/Cas9 technology. This CpG island contains a bidirectional promoter for Hoxd1 and Haglr and also encompasses the first exons of both genes. (J:252916)