这个转基因包含了以下组件:人类角蛋白14的启动子,直到翻译起始点,人类胶原型Vα1的cDNA,以及KRT14的3' UTR序列,包括poly(A)信号。构建物被注入了受精卵卵母细胞的精子内核。免疫印迹和RT-PCR确认了这个转基因在表皮中驱动COL5A1的表达。(来源:J:189446)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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