这个靶向构建是针对SYNJ2BP基因内1号 intron,包含了CAG-loxP-neomycin (reversed)-pA-loxP-3xHA-EGFP-SYNJ2BP-lacZ-BGH-pA序列。3xHA-EGFP-SYNJ2BP部分是"MITO-Tag"组件,它将3XHA标签和GFP定位到线粒体膜上。构建仅包含rat Synj2bp/OMP25基因的外膜段(AA109-145)。内置的lacZ小片段预计功能上是无效的。(来源:J:268121)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6(Cg)-Tyrc-2J
Targeted
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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