这个靶向构建是针对SYNJ2BP基因内1号 intron,包含了CAG-loxP-neomycin (reversed)-pA-loxP-3xHA-EGFP-SYNJ2BP-lacZ-BGH-pA序列。3xHA-EGFP-SYNJ2BP部分是"MITO-Tag"组件,它将3XHA标签和GFP定位到线粒体膜上。构建仅包含rat Synj2bp/OMP25基因的外膜段(AA109-145)。内置的lacZ小片段预计功能上是无效的。(来源:J:268121)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count