这个靶向构建包含了a CAG启动子,一个被敲除的STOP cassette,连接了人类Kir2.1编码序列的mCherry报告基因,以及木鼠肝炎病毒的后转录调控元件(WPRE,用于提高mRNA的稳定性),以及polyadenylation序列。来源:(J:245007)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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