Exon 1和Exon 2被替换了带有IRES-tauGFP-LNL序列的元件。对粗脑提取物进行 Western blot 分析后,发现纯合小鼠中未检测到编码蛋白。(来源:J:262456)
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Exon 1 and exon 2 were replaecd with an IRES-tauGFP-LNL cassette. Western blot analysis on crude brain extracts showed that no detectable encoded protein was present in homozygous mice. (J:262456)