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中文
为了在exon 5引入突变，首先将一个含neo cassette的floxed序列插入到intron 4，然后通过Cre介导的重组移除。剩余的loxP座点导致了剪接异常，进而导致突变mRNA的非正常降解。(来源：J:228679)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
