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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Rela-luc)31Xen
Alias:
NFkappaB-RE-luc
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基础信息
表型特征
文献报道
在SV40基本启动子上游插入了6个NF-κB响应元件(RE)的构建,来自CMV(即时早期)启动子。这驱动了修改后的荧光素酶cDNA的普遍基础表达。LPS和TNF-α能诱导报告基因的表达增强。(来源:J:147112)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
6189106
BALB/cJ
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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