这种靶向构建在第3外显子引入了FRT位点、lacZ报告基因、loxP位点、诺卡因抗性基因座、再次的FRT位点和loxP位点。额外的loxP位点被插入在第5外显子下游。通过Flp介导的重组,移除了报告和选择元件,保留了第4和5外显子的loxP标记。来源:(J:263129)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129)F1
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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