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在exon 7，包含cp切割位点的区域，两侧有loxP位点。在lag3终止密码子和pA之间插入了ire-s-yfp。接着插入了一个FRT标记的诺卡因选择性 cassette，位于pA后面。通过cre介导去除exon 7后，这些小鼠预期将失去lag3的细胞表面表达，无法介导信号，但会继续分泌可溶性蛋白。(来源：J:260063)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
