从Col11a2基因转录起始点上游453bp的鼠标基因组序列,延伸到下游380bp(前者是启动子,后者是5' UTR序列),被克隆到了包含SV40内含子、lacZ报告基因和SV40poly(A)信号的构建中。这个构建被注入了F1 C57BL/6 C3H杂交鼠的受精卵核中。(来源:J:35420)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count