G突变为A的点突变导致第801位的天冬酰胺被精氨酸取代,这个位点的氨基酸变化被标记为D801N。这种突变不影响蛋白质的量,但降低了ATP酶活性54-80%。插入了FRT引导的诺卡因抗性基因 cassette。(来源:J:262419)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Single point
--
1
14
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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