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这个靶向载体设计时，包含了一段人类MIR125B1的cDNA，它被插入到了EGFP序列3'非翻译区的两个剪接位点之间，后面跟着一个polyA信号。然后，这个载体被用来替换小鼠胚胎干细胞系中的Cre ORF，置于tet响应驱动元件(TRE)的调控之下。构建通过诱导 cassette exchange (ICE)重组，被插入到了Hprt基因上游的 cassette exchange 遗传位点。(来源：J:240427)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
