CRISPR/cas9基因编辑通过引导RNA定向靶向Gt(ROSA)26Sor基因座的内含子1。构建了由非同源的attP锚定位点(如48bp的Bxb1 attP-GT序列、240bp的Gt(ROSA)26Sor序列的天然间隔区和48bp的Bxb1 attP-GA序列)环绕的寡核苷酸供体DNA。来源:(J:322700)
Basic Information
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count