在exon 2的上游插入了一个loxP位点,通过同源重组,通过homologous recombination在exon 2下游插入了FRT介导的neo cassette loxP位点、终止子 cassette和IRES-tdTomato报告基因。随后,通过Flp介导的重组去除了neo cassette。(来源:J:260033)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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