The transgenic construct contains a bidirectional CMV promoter with a tetracycline operator (tetO) site, pBiGNot1, directing expression of a b-galactosidase (lacZ) reporter followed by a b-globin polyA signal on one side and human ATP2B4 cDNA squence on the other side. (J:128144)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count