通过GENSAT修饰的细菌人工染色体(BAC)RP23-224O8,其编码增强绿色荧光蛋白(EGFP)的序列被插入到了小鼠神经前体细胞盒2(Nkx2.2)基因5'调控序列的下游,来自CHORI,然后用于对受精卵的精子核进行微注射。后代中, founder line 2 显示出了最强的EGFP表达。(来源:J:214964)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 or SJL
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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