这个IMPC的等位基因是在多伦多的表型基因组学中心通过Cas9蛋白和4个引导序列的注入产生的,具体序列包括CCTAGCATCTGGATTGTCTAGTT、CCAGCAGCTGTGCTTATCACATA、TAAGAGTGCCTTTGCATGCTTGG和CCTACAGGAACTGAATATTGGTA,导致了外显子的缺失。(来源:J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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