这个来自TCPR0434项目的等位基因是在phenogenomics中心通过向细胞注射Cas9 mRNA和四种引导RNA,这些RNA带有ACTACCCTGGTTGGACTGGC和GCAATCATCCCCTATATCTC的 spacer序列,目标是染色体7的5'端,以及CCCTCTTAAGAACTCTTTTC和ATTGACAGTGCCAAGAAAGT针对3'端的ENSMUSE00000531437(也就是基因2的exon 2),产生了772bp的染色体7缺失,位置从48,020,898到48,021,669(GRCm38建库)。(引用:J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部