他来自TCPR0921项目的一个等位基因是在phenogenomics中心通过电穿孔,使用了带有ATACCATCCTACACCAGACT和AGGAATGGATCAATCCACGC这两条3'侧导向的单链RNA指导的Cas9核糖核酸蛋白复合物,目标区域是5'端,以及TGATTCAACTTTAAAGACGG和GGAGAACAAGTCAGTGACGA这两条5'侧导向的,产生了一个841bp的缺失,位置在chr1:52640700到52641540(GRCm38)。(引用信息:J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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