这个来自TCPR0855项目的等位基因是在表型基因组学中心通过电穿孔,使用了带有TGTGCACGAAATCTACAGTG、TAATCCAGGGGCAGTGCCAA和CCGAACCAGCACCACTGGTG间隔序列的Cas9核糖核酸蛋白复合物,产生的。这导致了16个碱基的删除,位置在chr11:60865301至60865316,具体变异为_TGCACGAAATCTACAG; c.89_104缺失(TGCACGAAATCTACAG);以及p.H31G*fs23(GRCm38建库)。(引用信息:J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
插入,基因内删除
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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