这个等位基因是在表型遗传学中心通过电穿孔方式,用含有GATGAGGACCTAGGTGGGTG和GCTTCCTTAGGATACTAAGC这两种单链RNA指导的Cas9核糖核酸复合物,针对基因ENSMUSE00000325812的5'端以及ENSMUSE00001242969的3'端,产生了473bp的缺失。变异位置位于染色体6的23114817-23115289,插入了GCATCAAGTGTTT序列,基因组参照为GRCm39。(来源:J:237616)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
基因内删除
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1
2
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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