这个靶向载体被设计成在基因的3'端插入一个血小板凝集素(HA)标签,接着是一个内源性核糖体进入信号(IRES)连接到增强型红色荧光蛋白(tdTomato)序列。载体中还包含一个由loxP位点标记的诺如选择素(neo)元件。通过Cre介导的重组,会去除这个neo元件。(来源:J:305328)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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