将包含一段10,389bp的 mouse Gad2 基因exon 16的基因组DNA片段,以及插入在终止密码子TAA和3' UTR之间的IRES-FlpO-loxP2272-ACE-Cre POII NeoR-loxp2272 cassette的靶向载体,导入ES细胞中。阳性ES克隆经扩增后,用于产生经过NeoR cassette自噬的嵌合小鼠。(来源:J:261454)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6J)F1
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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