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Cas9 mRNA和单链向导RNA(sgRNA)，针对exon 2的位置，被注入到受精卵阶段胚胎的细胞质中，以诱发删除。注射后的胚胎被植入CD-1代孕小鼠中，然后对幼崽进行删除性突变的筛选。两个系得到了。这个突变体包含一个71bp的删除，包括起始密码子和催化保守的Cys2密码子。(来源：J:254234)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
