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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Mtcl1
tm1.1Atsuz
Alias:
Mtcl1
flox
1110012J17Rik(loxP)
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基础信息
表型特征
文献报道
Exon 1被LoxP序列包裹,随后在内含子1插入了一个由FRT序列引导的诺卡因抗性基因座。通过后续的Flp介导重组,这个诺卡因基因座被去除了,从而产生了一个Exon 1敲除的条件性可操作等位基因。(来源:J:253309)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6154024
Not Specified
Targeted
插入
--
1
1
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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