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中文
在exon 1上游插入了loxP位点，接着是带有FRT标记的诺卡因抗性基因，再在exon 1下游插入了另一个loxP位点。通过Flp介导的重组去除了选择性元件。随后，Cre介导的重组切除了exon 1。实时PCR证实了mRNA转录的完全丢失，免疫组化则确认了脑部中没有蛋白质存在。(来源：J:250058)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
