L1L2_Bact_P cassette,包含FRT-En2剪接接受器(SA)-IRES-lacZ-SV40poly(A)信号(pA)-loxP人类β-actin启动子-neoR-SV40poly(A)信号(pA)-FRT-loxP序列,被插入到exon 3上游,且在exon 3下游额外增加了一个loxP位点(位置152817361)。通过Cre介导的重组,去除了含floxed neo的元件和exon 3。在同源纯合子的粒细胞匀浆中, Western blot分析未检测到基因产物(蛋白质)。(来源:J:260777)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入,基因内删除
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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