Fgfr2-IIIc编码序列被克隆到了一个包含PGK-Neo选择标记和tpA转录终止序列的载体中,这个载体带有floxed cassette。通过同源重组,这个构建被插入到了目标位点。当Cre介导去除选择标记和终止序列后,IIIc亚型会在Gt(ROSA)26Sor启动子的调控下进行转录。(来源:J:261451)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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