这种转基因是通过人类RHD红细胞膜蛋白的cDNA,受控于特异的β-珠蛋白启动子和LCR元件。在没有人类RHAG蛋白的情况下,人源蛋白在红细胞上未检测到。当与表达RHAG蛋白的转基因小鼠一起表达时,会观察到(较低的)人类RHD抗原表达水平。(来源:J:209676)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x CBA
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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