这段基因的3575bp由loxP位点 flank,包括1到3号外显子和基因的启动子区域。5'的loxP位点与一个1014bp上游的FRT-介导的诺卡因选择 cassette一起插入,3'的loxP位点位于3号外显子后247bp的位置。FRT-介导的诺卡因选择 cassette在小鼠中通过Flp介导的重组被剔除。(来源:J:237676)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/Ola
Targeted
插入
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1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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