在exon 2前方的379bp位置插入了含有工程改造的ApaLI和Bcl座标,随后在exon 4后方的255bp处插入了FRT座标、loxP座标、诺卡因选择座标、再次的FRT座标以及loxP座标。通过Flp介导的重组,去除了选择座标,使得exons 2-4区域被标记为可剪接。(来源:J:233322)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入
--
1
1
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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