在exon 1前方约900bp位置插入了loxP位点,而在exon 2后方120bp处插入了含loxP标记的诺卡因抗性基因 cassette。Cre重组酶去除了选择性 cassette,保留了exons 1和2,编码蛋白质的前33个氨基酸,两侧由loxP位点环绕。这个等位基因来源于与Col15a1tm1Pih相同的靶向事件。(来源:J:67212)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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