从Tn(sb-SBlac)15.176598Fsp转基因小鼠中,使用未知来源的TgTn(sb-SBlac)15Fsp转基因小鼠的Sleeping Beauty转座酶进行转座,成功将转座子整合到了染色体15上,具体位置在15号染色体15:63590844-63590845(GRCm39),方向为正向。转座子包含Sleeping Beauty转座子的倒置重复、loxP位点、人类β-珠蛋白的HBB最小启动子、lacZβ-半乳糖苷酶报告基因、SV40的poly(A)信号序列,以及Sleeping Beauty转座子的直接重复。来源:(J:180121)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Transposon induced
转座子插入
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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