这个转基因构建包含一个5.4kb的murine Myh6启动子,驱动表达mouse hydroxysteroid 11-beta dehydrogenase 2(Hsd11b2)的cDNA,后面跟着人类生长激素和polyadenylation序列。Founder line 326拥有29个这种转基因拷贝。(来源:J:258076)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count