这个构建包含了由CMV启动子驱动的Kdm2b cDNA,连接了一个tet响应元件(tetO),并通过电穿孔转入KH2胚胎干细胞。同时,还伴随一个表达Flpe重组酶的质粒,以便通过FRT/Flp酶介导在特定位置实现单拷贝的定点整合。(来源:J:232437)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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