CreERT2-pA-FRT-Neo-FRT被插入到Trp63基因的第4外显子,导致Trp63蛋白isoform在第115位氨基酸后形成一个框内融合。雄性嵌合体小鼠与雌性FLPeR小鼠杂交,以去除Frt-flanked的PGK-neo cassette。(来源:J:249188)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count