在exon 1上游插入了loxP位点,随后通过同源重组插入了一个包含FRT 6.5、polyA序列、loxP位点、neo cassette、FRT位点和另一个loxP位点的构建。通过Flp介导的重组,移除了polyA序列和neo cassette,使得exons 1和2被标记为可删除的(来源:J:256465)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部