Cas9和引导序列GTACATCTCTGTCGGCTATG针对H2-D1b,ATAATCCGAGATTTGAGCCG针对H2-K1d,被注入到NOD/ShiLtDvs胚胎中,导致了二个exon 2的缺失,一个11bp,另一个3bp,以及单个碱基的H2-K1em1Dvs变异。(来源:J:257229)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
NOD/ShiLtDvs
Endonuclease-mediated
基因内删除
不确定
1
12
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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