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中文
CRISPR引导的工具将TGT替换成CGT，导致第5外显子的氨基酸替换，从arginine变为 cysteine（C284R）。这个等位基因模拟了人类患青少年型脊柱关节炎和早发型克罗恩病的‘风险’变异（J:244365）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
