Exon 7被替换成经过修改的7到11号外显子,去除了248到337位氨基酸,后面跟着Flag-HA标签、转录终止、FRT引导的诺卡因抗性基因座,接着是一个LoxP位点。通过Flpe介导的重组移除了诺卡因基因座。两个胶原重复区域都被删除了。(来源:J:249238)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
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1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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