目标向量包含T2A肽-Cre-rabbitβ-珠蛋白polyA-FRT-Neo cassette-FRT,插入位置位于小鼠Map3k15基因的终止密码子之前,BAC(RP24-211E22)中进行了电穿孔处理,然后在ES细胞中。抗性克隆经筛选和确认为同源重组合适。阳性克隆被选中并确认,阳性ES细胞被注入BALB/C小鼠的囊胚中,以产生嵌合体小鼠。(来源:J:255343)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部