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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gt(ROSA)26Sor
tm1(Thy1-MAPT*A152T)1Eman
Alias:
hTau
AT
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基础信息
表型特征
文献报道
在J:234422中,描述的是一种构建,它利用了特异性的神经元标记物Thy1.2的启动子,驱动了携带渐进性超大脑皮层萎缩相关突变p.A152T的完整人类MAPT(tau)基因的表达。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
6117407
C57BL/6NTac
Targeted
插入
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--
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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