Log In|Sign Up
中文
这个突变是在Jackson实验室通过向细胞注射Cas9 RNA和四种指导序列（GCATTTAGTGGCAGAGGGAA、CCTTTCTTATTCTGTCAGCG、ATGTACACGGGAAAAGACCA和ACACGGGAAAAGACCATGGC）产生的，导致了从染色体4正链42,956,466bp开始，到42,957,240bp之后的775bp区域缺失。这个变异删除了ENSMUSE00001313254（第3外显子）以及173bp的内含子序列，包括剪接点的接受者和供体，预测会导致第71位氨基酸之后序列改变，并且随后有11个早期终止密码子。（来源：J:188991）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
